Welcome to the sidoli lab

Our lab develops mass spectrometry for chromatin biology. We implement and apply new quantitative methods to define the state and dynamics of chromatin in health and other conditions. We are also invested in innovating new 3D cell models to reduce the necessity of animal testing.

December 2025

All news

A huge congratulations to Shivangi!! After many months of wait, she finally obtained her AHA grant! Amazing work! That is really great, but also a little bittersweet; since the Sidoli Lab is not expert in cardiac research, she will use this grant to join the Dr. Gaetano Santulli Lab (CUNY) for her postdoc. We will miss her very much next year.

What a rollercoaster month in terms of publications! The lab produced some amazing work, which is finally out! (i) Giulia and Ronnie’s single cell histone analysis protocol is finally out in JoVE (link). (ii) Our work demonstrating that histone succinylation is enriched in progeny of centenarians, and that succinate improves some health parameters in mice, is out in Aging Cell! Congratulations to Stephanie and Sarah (link). (iii) Jenny and Carlos led a work in collaboration with Merck on high-throughput analysis of antibody-drug conjugates, which is out in ACS Pharmacology and Translational Science (link). Holy wow, December!!

Welcome to the lab to Charlotte Thomas! Charlotte joins us as rotation student for the period December-February 2026 (included).

A huge number of collaborative papers coming out in December. Here is a list:

(i) Congrats to Sarah for her collaboration with the Huffman lab (Einstein) just accepted in Scientific Reports! Title: "Reduced IGF-1 signaling fails to limit Alzheimer’s disease progression in a novel rat model of IGF-1R haploinsufficiency" (link).

(ii) Congrats to Stephanie for a new collaboration with the Alani lab (Boston University) published in JCI Insight (link).

(iii) Stephanie again for her new collaboration with the Morey lab (U Miami) out in Genes & Development (link).

(iv) Finally, congratulations to Ronnie for his collaboration with the Ana Maria Cuervo lab (Einstein) on chaperone-mediated autophagy in neurons published in Nature Cell Biology (link).

New lab pictures at this link and below! And pictures from our “End-of-the-year” lab lunch (link)!

 

Latest images

All images
Some behind the scenes of Giulia’s and Ronnie’s JoVE protocol 🎬🎬🎬🎞️🎞️🎞️📽️📽️📽️
Some behind the scenes of Giulia’s and Ronnie’s JoVE protocol 🎬🎬🎬🎞️🎞️🎞️📽️📽️📽️
New Sidoli lab picture ❤️❤️❤️
New Sidoli lab picture ❤️❤️❤️
Hot pot lab lunch! 🫕🫕🫕🫕
Hot pot lab lunch! 🫕🫕🫕🫕
😂😂😂
😂😂😂
The Ullmann building peaking from the snow ❄️❄️❄️❄️❄️
The Ullmann building peaking from the snow ❄️❄️❄️❄️❄️
Who is there??!! 😂😂😂
Who is there??!! 😂😂😂
Caught them in the act of robbing other labs 😂😂😂💸💸💸
Caught them in the act of robbing other labs 😂😂😂💸💸💸
The lab is feeling on holiday already 🎄🎄🎄🎄🎄🎄🎄🎄🎄
The lab is feeling on holiday already 🎄🎄🎄🎄🎄🎄🎄🎄🎄
Giulia and Ronnie filming their JoVE protocol on single cell histone prep! 🤩🤩🤩🤩🤩
Giulia and Ronnie filming their JoVE protocol on single cell histone prep! 🤩🤩🤩🤩🤩
The perks of reviewing for grants in Switzerland 🇨🇭🇨🇭🇨🇭 Thank you ETH Zurich for making our day 🍫🍫🍫
The perks of reviewing for grants in Switzerland 🇨🇭🇨🇭🇨🇭 Thank you ETH Zurich for making our day 🍫🍫🍫
Amazing Epigenetics Symposium today at MSKCC! So nice to see old friends. Congratulations to the organizers, and great that most of the Sidoli Lab could attend 😊
Amazing Epigenetics Symposium today at MSKCC! So nice to see old friends. Congratulations to the organizers, and great that most of the Sidoli Lab could attend 😊
You walk around the Einstein bridges, and then this view appears 😍😍😍
You walk around the Einstein bridges, and then this view appears 😍😍😍
Need to improvise a glove box to aliquot without oxygen? No problem 😉😉😉😉😉
Need to improvise a glove box to aliquot without oxygen? No problem 😉😉😉😉😉
So exciting to read books from your colleagues next door 🥰🥰🥰
So exciting to read books from your colleagues next door 🥰🥰🥰
Are you interested in reviewing papers in Analytical Biochemistry (for your CV, civil duty, or any other reason)? Feel free to DM us! Simone is now acting as Executive Editor, and looking to expand our network of reviewers!
Are you interested in reviewing papers in Analytical Biochemistry (for your CV, civil duty, or any other reason)? Feel free to DM us! Simone is now acting as Executive Editor, and looking to expand our network of reviewers!
Some behind the scenes of Giulia’s and Ronnie’s JoVE protocol 🎬🎬🎬🎞️🎞️🎞️📽️📽️📽️ New Sidoli lab picture ❤️❤️❤️ Hot pot lab lunch! 🫕🫕🫕🫕 😂😂😂 The Ullmann building peaking from the snow ❄️❄️❄️❄️❄️ Who is there??!! 😂😂😂 Caught them in the act of robbing other labs 😂😂😂💸💸💸 The lab is feeling on holiday already 🎄🎄🎄🎄🎄🎄🎄🎄🎄 Giulia and Ronnie filming their JoVE protocol on single cell histone prep! 🤩🤩🤩🤩🤩 The perks of reviewing for grants in Switzerland 🇨🇭🇨🇭🇨🇭 Thank you ETH Zurich for making our day 🍫🍫🍫 Amazing Epigenetics Symposium today at MSKCC! So nice to see old friends. Congratulations to the organizers, and great that most of the Sidoli Lab could attend 😊 You walk around the Einstein bridges, and then this view appears 😍😍😍 Need to improvise a glove box to aliquot without oxygen? No problem 😉😉😉😉😉 So exciting to read books from your colleagues next door 🥰🥰🥰 Are you interested in reviewing papers in Analytical Biochemistry (for your CV, civil duty, or any other reason)? Feel free to DM us! Simone is now acting as Executive Editor, and looking to expand our network of reviewers!